Extended lipid profile and urine albumin-creatinine ratio in type 2 diabetes mellitus

Background: Diabetes is a chronic metabolic disorder and has become the one of most challenging global health problem 21 st centuary. Diabetic nephropathy major complication diabetes an established risk factor for cardiovascular events. Lipid abnormalities occur in patients with diabetic nephropathy, which further increase their We aimed to research association between extended lipid profile urine albumin-creatinine ratio (UACR), hypothesizing that early detection treatment can minimize atherogenic cerebrovascular accident type 2 mellitus. Methods: A hospital based cross- sectional study was conducted on 48 All fasting blood glucose (FBG), HbA1c, total cholesterol (TC), high density lipoprotein (HDL), low (LDL), triglyceride (TG), apolipoprotein-A (apo-A), apolipoprotein-B (apo-B), (a){Lp(a)} urine-albumin creatinine (UACR) evaluated. Patients taking steroids, any renal disease other than uncontrolled hypertension were excluded from study. Based UACR level divided into three sub groups: normal (<30 mg/g), microalbumiuria (30-300 mg/g) macroalbuminuria (>30 mg/g). Comparison subgroups made using non parametric test (Kruskal Willis Test). Fisher’s exact used explore profile. Result: 20.8% had UACR<30 mg/g, 54.2% UACR:30-300 25.0% UACR:≥300 mg/g; 62.5% Lipoprotein(a): <30 mg/dl 37.5% > 30 mg/g. Significant found · 100.0% [UACR: mg/g] [Lipoprotein-a: <30mg/dL]. 57.7% 30-300 mg/dL]. 42.3% ≥30 41.7% >300 58.3% Conclusion: The showed resulting raised significant increased (a) consequently atherosclerotic (ASCVD). Since Lipoprotein(a) investigation not widely available, accessible varied estimation technique, be as marker ASCVD place DM.